Medicinal, Psychological, and Health Research Journal (MPHRJ)

Abstract Introduction: Acute postoperative pain remains a common concern following laparoscopic hysterectomy despite its minimally invasive nature. Pain severity is influenced by a complex interplay of patient characteristics, preexisting pain, psychological factors, surgical technique, and perioperative management. Identifying high‑risk patients is essential for optimizing analgesic strategies, enhancing recovery, and preventing long‑term pain‑related complications.

Material and methods: This observational study prospectively collected demographic and perioperative clinical data and followed patients through structured telephone interviews up to six months after surgery. Acute and chronic postoperative pain were assessed using validated numeric scales, alongside analgesic use and functional impact, allowing comprehensive evaluation of pain severity, distribution, and its influence on daily activities.

Results: In this cohort of women undergoing laparoscopic hysterectomy, postoperative pain declined progressively over time, with most patients achieving minimal pain by six months. Although chronic postsurgical pain affected a minority, pelvic and incisional pain predominated. Analgesic requirements varied, while functional impairment was generally limited, highlighting favorable pain recovery trajectories overall.

Conclusion: these findings reinforce the effectiveness of laparoscopic hysterectomy as a minimally invasive procedure with generally favorable pain and functional outcomes, while also highlighting the complexity of pain recovery in a minority of patients.

Abstract Introduction: Pediatric abdominal surgery is associated with significant postoperative morbidity, influenced not only by surgical factors but also by perioperative anesthetic management. Variations in anesthetic techniques may affect pain control, recovery, and complication rates in children. Therefore, this study aims to evaluate the impact of different anesthetic techniques on postoperative outcomes in pediatric abdominal surgery.

Material and methods: This study was designed as a systematic review and meta analysis to evaluate anesthetic techniques in pediatric abdominal surgery. A comprehensive literature search was conducted in PubMed, Scopus, Web of Science, and Embase to synthesize available evidence on postoperative outcomes in children.

Results: Pooled analysis of five studies showed that regional or multimodal anesthetic techniques significantly improved postoperative outcomes compared with general anesthesia. These approaches reduced pain intensity (SMD = −0.82, 95% CI −1.15 to −0.49; I² = 42%) and shortened hospital stay (MD = −1.34 days, 95% CI −1.98 to −0.70; I² = 46%), indicating consistent clinical benefits.

Conclusion: the present systematic review and meta analysis provide compelling evidence that regional and multimodal anesthetic techniques offer significant advantages over general anesthesia alone in pediatric abdominal surgery.

Abstract Introduction: Critically ill patients with COVID 19 exhibit a pronounced hypercoagulable state, predisposing them to deep vein thrombosis during ICU admission. Inflammation driven endothelial dysfunction, hypoxia, and immobilization contribute to this elevated risk. Determining the true prevalence of DVT in this population is essential for optimizing thromboprophylaxis strategies and improving clinical outcomes.

Material and methods: This retrospective observational study evaluated critically ill patients with concurrent COVID 19 and active malignancy admitted to a tertiary ICU. Clinical records, laboratory parameters, and imaging confirmed thrombotic events were systematically analyzed. Multivariable logistic regression was applied to identify independent risk factors for vascular thrombosis, providing clinically relevant insights for risk stratification and management in this high risk population.

Results: Thrombotic complications occurred in 28.3% of critically ill ICU patients with concurrent COVID 19 and active malignancy, while 71.7% remained free of thrombosis (P < 0.001). Among affected patients, venous thromboembolism predominated, with lower extremity deep vein thrombosis and pulmonary embolism being the most frequent manifestations, whereas arterial, cerebral, and coronary events were uncommon.

Conclusion: In conclusion, thrombotic complications remain a common and clinically significant problem among ICU patients with concurrent COVID 19 and active malignancy. Venous thromboembolism predominates, and its occurrence is associated with older age, higher BMI, specific cancer types, greater comorbidity burden, prolonged ICU stay, increased need for mechanical ventilation, and higher mortality.