Medicinal, Psychological, and Health Research Journal (MPHRJ)

Hemodynamic Effects and Complications of Bone Cement Utilization in Orthopedic Operations

Document Type : Original Article

Authors

Yashar Eslampoor 1
Naghi Abedini 2

1 Assistant Professor of Anesthesiology, Department of Anesthesiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

2 Associate Professor of Anesthesiology, Department of Anesthesiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

https://doi.org/10.22034/mphrj.2026.586278.1099
Abstract
Introduction: In contemporary orthopedic practice, bone cement continues to play a vital role in achieving successful surgical outcomes and improving patient mobility and quality of life. Nevertheless, its utilization is accompanied by important physiological effects that demand careful consideration. Hemodynamic changes associated with bone cement application represent a significant perioperative challenge due to their unpredictable nature and potential severity.

Material and methods: This prospective observational study was conducted at Shohada Hospital in 2025 to evaluate hemodynamic changes and complications associated with bone cement use during orthopedic surgery. A total of 200 patients were enrolled through convenience sampling. Perioperative cardiovascular and respiratory parameters were continuously monitored and recorded at predefined intervals.

Results: Among 200 patients undergoing cemented orthopedic surgery, hypotension was the most common intraoperative complication (29.00%), followed by tachycardia (20.50%) and hypertension (17.00%). Suspected Bone Cement Implantation Syndrome (BCIS) occurred in 11.00% of cases, while severe Grade 3 BCIS was identified in 1.00% of patients. Hemodynamic complications were significantly associated with older age, higher ASA class, cardiovascular comorbidities, prolonged surgery duration, and the use of general anesthesia.

Conclusion: Bone cement utilization in orthopedic procedures is associated with clinically important hemodynamic alterations and varying degrees of BCIS. Although most complications were transient and manageable, elderly patients and those with significant comorbidities demonstrated a higher risk of perioperative instability.

Graphical Abstract

Hemodynamic Effects and Complications of Bone Cement Utilization in Orthopedic Operations

Keywords

Bone Cement
Hemodynamic Instability
Bone Cement Implantation Syndrome
Orthopedic Surgery
Intraoperative Complications
Subjects
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Medicinal, Psychological, and Health Research Journal (MPHRJ)
Volume 2, Issue 4
July and August 2026
Pages 317-328

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