Medicinal, Psychological, and Health Research Journal (MPHRJ)

Abstract The aesthetic rejuvenation of the lower third of the face, particularly the jawline, has become a pivotal focus in modern cosmetic dermatology. This study introduces “Contouring Plus,” a novel, minimally invasive approach that combines the biostimulatory properties of Calcium Hydroxylapatite (CaHA) with the versatile volumizing and contouring capabilities of Hyaluronic Acid (HA) fillers. The protocol involves a strategic layering technique where CaHA is injected supraperiosteally along the mandibular border to provide structural support and stimulate neocollagenesis, while HA fillers are administered in the subcutaneous plane to refine contours and enhance soft tissue projection. The article presents a case series involving four patients aged 29 to 54, treated in a single session and evaluated over a 90-day period using clinical photography and three-dimensional imaging. Results demonstrated significant improvement in jawline definition and patient satisfaction, with minimal adverse events such as mild bruising and swelling. The safety profile is supported by adherence to precise anatomical landmarks and injection planes, minimizing risks of vascular complications. The combined filler technique capitalizes on the long-term collagen-stimulating effects of CaHA alongside the immediate, moldable benefits of HA, resulting in durable and natural-looking facial rejuvenation. This hybrid approach provides clinicians with an evidence-based, adaptable protocol for addressing age-related volume loss and contour irregularities in the lower face. Future studies are warranted to assess long-term outcomes and optimize filler combinations.

Abstract Background and Objective: Pneumonia is an inflammatory respiratory disease that can affect the patient's adaptive patterns. Nurses play a key role in facilitating the adaptation process of the patient. Therefore, this study aimed to explore the use of Roy’s Adaptation Model in the care of a patient with pneumonia.

Materials and Methods: This case report study was conducted in May 2025 at a hospital in Lahore, focusing on a patient with pneumonia. Nursing care based on the Roy’s Adaptation Model was implemented in six stages according to the nursing process.

Results: The results showed a significant reduction in the patient's maladaptive behaviors across four modes: physiological, self-concept, role function, and interdependence and independence.

Conclusion: Nursing care based on the Roy's Adaptation Model effectively reduced maladaptive behaviors in patients with pneumonia. Therefore, the implementation of organized nursing care based on appropriate nursing models is essential to improve patient health.

Abstract The use of injectable fillers in aesthetic medicine has gained significant popularity for facial rejuvenation and contouring. A crucial factor in achieving optimal results lies in understanding the patient’s unique facial shape, as it influences filler selection, injection technique, and treatment goals. This review explores the classification of facial shapes—commonly categorized as oval, round, square, heart, and diamond—and their implications for planning injectable filler treatments. Each facial shape presents distinct anatomical features and aesthetic challenges that must be addressed to restore harmony and balance. For example, oval faces typically require subtle volumization to maintain natural contours, while square faces may benefit from softening the jawline. Treatment strategies are tailored to enhance facial proportions, improve symmetry, and correct age-related volume loss. The integration of facial shape analysis with patient-specific factors such as skin quality, bone structure, and aging patterns facilitates a personalized approach to filler application. Additionally, understanding facial shape helps in predicting potential complications and managing patient expectations. This paper emphasizes the importance of a comprehensive facial assessment and individualized treatment planning to maximize the efficacy and safety of injectable fillers. By aligning treatment techniques with facial morphology, clinicians can achieve more natural, balanced, and aesthetically pleasing outcomes, ultimately enhancing patient satisfaction.

Abstract Structural facial rejuvenation with dermal fillers has become a cornerstone in non-surgical aesthetic treatments, particularly for women seeking natural, youthful, and harmonious facial contours. This approach focuses on restoring volume loss and supporting the underlying facial architecture rather than simply filling superficial wrinkles. By targeting key structural areas such as the midface, cheeks, jawline, and temples, practitioners can effectively counteract the effects of aging, including soft tissue descent, bone resorption, and fat compartment atrophy. The use of hyaluronic acid-based fillers and calcium hydroxylapatite has demonstrated safety, biocompatibility, and long-lasting outcomes in volumizing and lifting facial tissues. This method emphasizes a comprehensive understanding of facial anatomy, aging dynamics, and individualized treatment planning to achieve balanced and natural-looking results. Moreover, recent advances in imaging technologies and injection techniques have enhanced precision and minimized risks such as vascular complications and irregularities. Clinical studies support the efficacy of structural rejuvenation, reporting high patient satisfaction and improved facial aesthetics. However, successful outcomes require skilled assessment, tailored protocols, and an integrative approach combining filler use with other modalities when necessary. This article reviews current concepts, materials, and procedural strategies for structural facial rejuvenation in women, highlighting the importance of a holistic and anatomically informed technique to restore youthful facial contours safely and effectively.

Abstract Hospital laboratories play a fundamental role in ensuring timely and accurate diagnostic information that supports clinical decision-making and patient care. However, laboratory processes—such as specimen collection, handling, analysis, and reporting—are inherently complex and susceptible to various errors that may compromise patient safety and treatment outcomes. Failure Mode and Effects Analysis (FMEA) is a structured, proactive risk assessment tool that allows healthcare institutions to systematically identify, evaluate, and mitigate potential failures within critical workflows. This paper examines the application of FMEA in the context of hospital laboratory risk management. Through process mapping and collaboration among multidisciplinary teams—including laboratory staff, clinicians, and quality managers—potential failure modes were identified across different laboratory phases. Each failure mode was analyzed using a standardized scoring system for severity (S), occurrence (O), and detectability (D), leading to the calculation of a Risk Priority Number (RPN). High-priority risks such as sample mislabeling, equipment malfunction, and reagent expiration were addressed with targeted interventions, including barcode implementation, enhanced equipment maintenance protocols, and improved inventory systems. The findings indicate that FMEA significantly improves error detection and prevention in laboratory operations, promotes a culture of safety, and enhances compliance with international quality standards such as ISO 15189. Moreover, the participatory nature of FMEA fosters organizational learning and continuous quality improvement. Despite requiring time and training investment, FMEA offers a cost-effective approach to reducing diagnostic errors and improving patient outcomes. The study recommends routine application of FMEA and its integration with digital health technologies for real-time risk monitoring in clinical laboratories.

Abstract Introduction: The choice between regional and general anesthesia for inguinal hernia repair is of significant clinical importance, as it directly impacts postoperative pain, complication rates, recovery trajectories, and long-term patient outcomes. With increasing emphasis on individualized care and enhanced recovery protocols, determining the most effective anesthetic approach is essential to optimizing surgical results, minimizing adverse effects, and improving patient satisfaction, particularly in high-volume procedures with substantial global health implications.

Material and methods: This systematic review assessed the impact of regional versus general anesthesia on postoperative pain and complications following inguinal hernia repair. Using predefined criteria, relevant studies were identified through comprehensive database searches. Data were extracted on pain scores, complications, and recovery outcomes. Risk of bias was evaluated with validated tools, and meta-analyses with subgroup analyses addressed heterogeneity.

Results: This systematic review analyzed five studies comparing regional and general anesthesia in inguinal hernia repair. Regional anesthesia, particularly spinal, was associated with significantly lower postoperative pain scores and shorter hospital stays. While general anesthesia showed higher rates of nausea and vomiting, regional techniques were linked to a greater incidence of urinary retention.

Conclusion: Regional anesthesia for inguinal hernia repair provides superior postoperative pain control and reduces nausea and vomiting compared to general anesthesia. Although urinary retention is more frequent with regional techniques, overall complication rates remain low.

Abstract Introduction: Early detection of lung cancer can be effective in the treatment process. However, it is difficult to detect this cancer in its early stages. Because its symptoms are similar to a respiratory infection.

Material and method: In the current study, the issue investigated by reviewing 42 articles and considering key words such as "radiological images", "diagnosis", "airway tumors", "clinical care", “Systematic Review” in Scopus, Google scholar and PubMed databases.

Findings: Lung cancer treatments are designed to get rid of the cancer in the body or slow its growth. Treatments can eliminate cancer cells, help destroy them, or prevent them from multiplying, or teach your immune system to fight them. Some treatments are also used to reduce symptoms and relieve pain. Your treatment will depend on the type of lung cancer, its location, how far it has spread, and many other factors.

Conclusion: Graphene oxide was prepared using the Hammer method. The structural integrity of the synthesized graphene oxide was verified and confirmed using FT-IR, UV-Vis spectroscopies, and TEM imaging. The different responses of the biosensor Nano sensor to healthy and mutated DNA enabled the detection of lung cancer. Therefore, by relying on nanotechnology, it is possible to detect lung cancer through fast, easy and cost-effective methods.