Medicinal, Psychological, and Health Research Journal (MPHRJ)

Abstract Introduction: Acute postoperative pain remains a common concern following laparoscopic hysterectomy despite its minimally invasive nature. Pain severity is influenced by a complex interplay of patient characteristics, preexisting pain, psychological factors, surgical technique, and perioperative management. Identifying high‑risk patients is essential for optimizing analgesic strategies, enhancing recovery, and preventing long‑term pain‑related complications.

Material and methods: This observational study prospectively collected demographic and perioperative clinical data and followed patients through structured telephone interviews up to six months after surgery. Acute and chronic postoperative pain were assessed using validated numeric scales, alongside analgesic use and functional impact, allowing comprehensive evaluation of pain severity, distribution, and its influence on daily activities.

Results: In this cohort of women undergoing laparoscopic hysterectomy, postoperative pain declined progressively over time, with most patients achieving minimal pain by six months. Although chronic postsurgical pain affected a minority, pelvic and incisional pain predominated. Analgesic requirements varied, while functional impairment was generally limited, highlighting favorable pain recovery trajectories overall.

Conclusion: these findings reinforce the effectiveness of laparoscopic hysterectomy as a minimally invasive procedure with generally favorable pain and functional outcomes, while also highlighting the complexity of pain recovery in a minority of patients.

Abstract Introduction: Post-thyroidectomy hemorrhage is a rare but serious complication that can lead to airway compromise and increased morbidity. Identifying the risk factors associated with postoperative bleeding is essential for optimizing patient selection, surgical techniques, and perioperative management. This systematic review aims to evaluate patient-related and surgical risk factors contributing to post-thyroidectomy hemorrhage.

Materials and Methods: A comprehensive systematic review was conducted following PRISMA guidelines. Studies assessing risk factors for post-thyroidectomy hemorrhage were retrieved from PubMed, Scopus, Web of Science, and Embase. Inclusion criteria encompassed observational studies and randomized controlled trials investigating hemorrhage-related factors. Data extraction included demographic characteristics, comorbidities, surgical details, and bleeding incidence. Statistical analyses were performed to determine the odds ratios (ORs) for significant predictors.

Results: A total of 27 studies involving 8,452 patients were analyzed. Key risk factors for hemorrhage included age >55 years (OR: 2.89, p<0.001), male sex (OR: 1.87, p=0.002), hypertension (OR: 3.21, p<0.001), diabetes (OR: 2.68, p<0.001), and anticoagulant use (OR: 3.02, p<0.001). Surgical factors, including total thyroidectomy (OR: 2.91, p<0.001), prolonged operative time >120 minutes (OR: 3.75, p<0.001), and surgeon inexperience (<100 cases, OR: 4.32, p<0.001), were strongly associated with increased bleeding risk.

Conclusion: Post-thyroidectomy hemorrhage is influenced by both patient and surgical factors. Identifying high-risk individuals, optimizing perioperative care, and ensuring surgical expertise can significantly reduce complications. Future research should focus on predictive models and improved hemostatic strategies.

Abstract Introduction: Hepatitis C Virus (HCV) infection remains a major concern among dialysis patients due to the high risk of nosocomial transmission. Despite advancements in infection control, significant variability in HCV prevalence persists across dialysis populations. Identifying key risk factors is essential for improving preventive strategies and patient outcomes.

Materials and Methods: This systematic review was conducted following PRISMA guidelines. A comprehensive literature search was performed in PubMed, Scopus, Web of Science, and Embase to identify studies assessing HCV risk factors in dialysis patients. Inclusion criteria encompassed observational studies in adult dialysis populations, while case reports and pediatric studies were excluded. Data on study characteristics, HCV prevalence, and associated risk factors were extracted and statistically analyzed.

Results: HCV prevalence among dialysis patients ranged from 9.38% to 15.04%. Key risk factors included prolonged dialysis duration (>5 years, OR: 3.45), history of blood transfusions (OR: 2.87), reuse of dialysis filters (OR: 2.42), inadequate infection control (OR: 4.12), and hemodialysis modality (OR: 1.89). Geographic variability in prevalence was also observed.

Conclusion: HCV transmission in dialysis patients is driven by multiple modifiable risk factors. Strengthening infection control measures, enhancing routine screening, and expanding access to antiviral therapies are crucial for reducing the burden of HCV in dialysis settings.